Can I Give My Dog Denamarin?

Yes, with care
SAMe + milk thistle (silybin) is commonly referenced for dogs at published doses. The published veterinary reference range for same + milk thistle (silybin) in dogs is 18-20 mg per kg of body weight, given every 24h. In practice: SAMe ~18-20 mg/kg on empty stomach; combo products by label weight band. Liver-support standard. Give 1h before food. Elevated liver values still need vet workup, this supports, it does not diagnose.
Source: Veterinary Partner (VIN)
Get the exact range for your dog's weight

The safe habit

Confirm any medication decision with your veterinarian, who knows your dog's health history and other medications. VetDose shows published reference data, not prescriptions.